About Hemophilia A

Hemophilia A is an inherited bleeding disorder in which a person’s blood does not clot properly. People with hemophilia A are missing or have low levels of certain clotting factors. Clotting factors are proteins that help blood clot. An effective clot is needed to seal wounds and stop bleeding. Lack of clotting factors puts a person at risk for longer bleeding episodes and other complications.

Hemophilia A & FVIII

Hemophilia A—the most common type—affects 1 in 5,000 males in the US. People with hemophilia A are missing a clotting factor called factor VIII (FVIII).1

Depending on how much factor VIII is missing, hemophilia A may be classified as mild, moderate, or severe. About 6 out of 10 people with hemophilia A have the severe form.2 The goal of treatment is to replace the missing factor VIII in order to stop and prevent bleeding.3

Click here to learn more about treatment of hemophilia A with Koāte-DVI »

 

References: 1. Castaldo G, D'Argenio V, Nardiello P, et al. Haemophilia A: molecular insights. Clin Chem Lab Med. 2007;45(4):450–461. 2. National Hemophilia Foundation website. Hemophilia A (factor VIII deficiency). www.hemophilia.org. Accessed September 17, 2014. 3. Dargaud Y, Negrier C. Haemophilia therapies. Expert Opin Biol Ther. 2007;7:651–663.